The Impact and Mechanism of Viagra (Sildenafil) in Erectile Dysfunction Treatment

231.00 $
Published date: 2025/05/04
  • Location: Pe17 9zd, Utah, United States
This relaxation allows for increased blood flow into the penile tissues, leading to an erection. Under normal conditions, upon sexual arousal, nitric oxide is released into the corpus cavernosum, part of the penis enlargement pump reviews structure. This nitric oxide stimulates the production of cyclic guanosine monophosphate (cGMP), a molecule that causes the smooth muscles in the penis to relax. The mechanism of action for Viagra involves the blocking of the PDE5 enzyme, which is predominantly found in the penis.

The active ingredient in Viagra, sildenafil, belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. However, during clinical trials in the early 1990s, an unexpected property of Viagra emerged—it significantly improved erectile function. Viagra, chemically known as sildenafil citrate, was initially developed for the treatment of hypertension and angina pectoris, a type of chest pain associated with coronary heart disease.

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